Omics Glossary

Comprehensive definitions of omics, mechanisms of action, and network analysis terms for life sciences researchers.

1. Omics Types

110 terms

genome
gene
allele
SNP
transcriptome
DNA sequencing
RNA-Seq
CRISPR
gene editing
variant calling
GWAS
epigenome
methylation
chromatin remodeling
histone mark
promoter
enhancer
intron
exon
transcription factor
miRNA
siRNA
noncoding RNA
copy number variation
structural variant
karyotype
linkage map
reference genome
base pair
codon
open reading frame
proteome
peptide
polypeptide
protein folding
post-translational modification
phosphorylation
ubiquitination
acetylation
mass spectrometry
2D-gel electrophoresis
LC-MS/MS
protein complex
chaperone
interactome
kinome
phosphoproteome
secretome
antibody
antigen
epitope
western blot
ELISA
immunoprecipitation
affinity tag
structural proteomics
metabolome
metabolite
lipidomics
glycomics
fluxomics
NMR spectroscopy
LC-MS
GC-MS
pathway analysis
metabolite profiling
biomarker discovery
metabolite network
energy metabolism
TCA cycle
glycolysis
oxidative phosphorylation
lipid biosynthesis
amino acid metabolism
xenobiotic metabolism
transcriptome
mRNA
splicing
isoform
RNA-Seq
qPCR
microarray
differential expression
transcript quantification
alternative splicing
RNA stability
transcription start site
promoter usage
polyadenylation
long noncoding RNA
DNA methylation
histone acetylation
chromatin state
nucleosome
chromatin accessibility
ATAC-Seq
ChIP-Seq
enhancer promoter interaction
CpG island
imprinting
epigenetic modification
microbiomics
viromics
exposomics
pharmacogenomics
nutrigenomics
connectomics
immunomics
single-cell omics
multi-omics integration

2. Mechanisms of Action

77 terms

ligand
receptor
agonist
antagonist
partial agonist
enzyme
substrate
cofactor
inhibitor
activator
binding affinity
Kd
EC50
IC50
allosteric site
catalytic triad
covalent bonding
GPCR
receptor tyrosine kinase
JAK-STAT pathway
MAPK cascade
PI3K/Akt
NF-κB activation
Wnt/β-catenin
Hedgehog
Notch
TGF-β
calcium signaling
cAMP
second messenger
phosphorylation cascade
feedback loop
cross-talk
gene expression regulation
apoptosis
autophagy
proliferation
differentiation
immune activation
cytokine release
inflammation
oxidative stress
DNA repair
cell cycle arrest
senescence
migration
angiogenesis
absorption
distribution
metabolism
excretion
ADME
pharmacokinetics
pharmacodynamics
bioavailability
half-life
therapeutic window
on-target effect
off-target effect
toxicity
synergy
antagonism
dose-response
receptor occupancy
molecular target
biological process
pathway node
upstream
downstream
effector
feedback
feedforward
cascade
signaling axis
checkpoint
regulator
modulator

3. Chain of Causality Frameworks

39 terms

4. Related Methodologies / Techniques

80 terms

cell culture
cloning
PCR
electrophoresis
western blot
flow cytometry
ELISA
microscopy
immunostaining
FISH
CRISPR-Cas9
RNA interference
transfection
viral vector
in vivo model
xenograft
organoid
bioreactor
next-generation sequencing
long-read sequencing
single-cell sequencing
nanopore
Illumina
Sanger
barcoding
library prep
hybrid capture
alignment
assembly
variant calling
annotation
normalization
clustering
PCA
t-SNE
UMAP
differential expression analysis
pathway enrichment
gene ontology
network analysis
machine learning
feature selection
dimensionality reduction
model validation
cross-validation
ROC curve
confusion matrix
molecular dynamics
docking
QSAR
homology modeling
systems biology modeling
agent-based model
rule-based simulation
ODE models
PDE models
Bayesian networks
probabilistic graphical models
causal inference
mechanistic modeling
hybrid AI models
heatmap
volcano plot
network graph
chord diagram
Sankey diagram
Cytoscape
pathway view
dashboard
data fusion
ontology mapping
FAIR data principles
metadata
provenance
version control
API
semantic web
RDF
SPARQL
knowledge graph embedding

5. Disease / Application Areas

41 terms

6. Analysis / Visualization Terms

60 terms

Start visualizing your research

Turn complex omics data into clear, interactive network visualizations.

Request Beta Access